Adjuvants that are efficacious immune stimulators for cancer antigens are a critical need for the advancement of cancer therapy. Spirulina has shown immense early potential for dendritic cell stimulation and T-cell activation through IL12p70, and IFN-d secretion, and cytotoxic T-cell stimulation. Future studies will investigate three other organic sources of Spirulina to understand the differences in components and efficacy based on those variables. We will then optimize the best spirulina extract, as an adjuvant candidate, into a cancer vaccine formulation.
Learning Objectives:
Primary objective was to measure the crosstalk between innate and adaptive immune system at varying concentrations of one blue-green Spirulina extract.
Secondary objective was to explore the differences between multiple sources of organic Spirulina available for purchase in the United States
This research highlights the immunostimulatory efficacy of an ethanolic spray-dried extract of Spirulina (Arthrospira platensis).
