PhD Student
University at Buffalo
Vincent Chak is a fifth-year PhD student at the University at Buffalo’s School of Pharmacy and Pharmaceutical Sciences. His research has been focus on
investigating immunomodulatory mechanisms of phosphatidylserine‑based lipid nanoparticles, with the goal of preventing aberrant immune responses to dietary antigens, mitigating autoimmunity, and enhancing the safety of biologic therapies. His research employed a comprehensive array of experimental approaches, including confocal fluoroscene microscopy, full‑spectrum flow cytometry, in vivo murine model experiment, predictive in vitro cell culture assays, and single-cell RNA sequencing, to elucidate how PS phosphatidylserine induce oral tolerance and the clinical application in PS mitigated unwanted immune responses.